RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
mir-29a
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
PCR; immunohistochemistry
Target
HH; MIRNA-29; NF-KB
Pathway
NF-KAPPA B SIGNALING PATHWAY
PubMed ID
Title
Potential role of Hedgehog signaling and microRNA-29 in liver fibrosis of IKKB-deficient mouse
Year
2014
Function
"When the nf-kb pathway is disrupted, the hh signal regulates the proliferation of mf-hscs, independent of mirna-29 expression, leading to hepatic fibrosis."